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 Measured parameters

 

• hERG assay

• Action Potential recordings in Purkinje fibers or papillary muscle

Supplementary parameters recorded in the following models :

- In atria

- In papillary muscle : Excitation-Contraction coupling

 

hERG assay

IC₅₀ values
Base current amplitude upon repolarisation to -40mV (Itail)
Leak current amplitude (Ibase)
Tail current amplitude : Itail- Ibase