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Partnership

FORMULATION ANALYSIS:

A GLP study must include a GLP experimental phase as well as GLP formulation analysis of the samples

• Development of a method in HPLC-UV or LCMS/MS in the vehicle
  
• Validation of a method for the assay of the test article in the vehicle used during PhysioStim GLP study
  

Specificity/Selectivity, linearity, accuracy and repeatability, stability of the solutions to be injected, stability of the formulations

• Formulations analysis

GENERAL PHARMACOLOGY: FOR A COMPLETE SAFETY PHARMACOLOGY PACKAGE

• ICH S7A - Core Battery Studies (CNS – Cardiovascular- Respiratory system)
• ICH S7A – Follow up studies (renal function- gastro intestinal system- endocrine system- coagulation)
  

HIGH THROUGHPUT SCREENING: FOR A LIBRARY OF COMPOUNDS

Correlation between electrophysiology data from PatchXpress automated patch-clamp platform and data obtained from conventional patch-clamp methods for rank-ordering compounds with known effects on hERG potassium channel.

• Automated patch-clamp platform enables multiple or parallel single-cell experiments for increased throughput
  
• Flexible testing protocols and timely data delivery
• Fully validated and quality-controlled