A history in excellence

Cardiovascular pharmacology & electrophysiology at its best

PhysioStim is an independent preclinical CRO with high-level expertise in the field of cardiovascular pharmacology and electrophysiology. The company was founded in 2000 by Dr. Marie Le Grand, our President, and is located in Lautrec south of France. Through PhysioStim, Dr. Le Grand aims to address the growing need of the pharmaceutical industry and biotech companies to conduct high quality preclinical assays and studies. Over the years, PhysioStim has grown into a highly valued team that rises to the challenge of designing and conducting high quality studies for drug development and validation. Our scientists are recognized for their expertise, reactivity, motivation and awarded with the loyalty of a consistently growing customer base.

“One-to-one customer relations are key to our business. We value our customers and guide their preclinical studies with innovative, robust ideas. Our main goal is to deliver state-of-the-art cardiovascular safety studies while providing excellent customer service.”



2000 Creation of Physiostim for microelectrode assays 2001 First GLP certificate 2003 GLP grade A certificate 2005 Launch patch clamp & hERG assays 2009 Launch of Langendorff assays 2013 Ethical committee animal experiments US006 / CREFRE 2015 Launch of isolated organ assays 2017 Alliance with Apconix 2018 PhysioStim completes a capital increase 2019 Launch of MEA/Impedance platform