A new model to study chronotropic effects

PhysioStim adds new model to study chronotropic effects

To check the cardiac safety of new drugs and compounds, PhysioStim has now added a new study model to detect potential chronotropic effects.

What are chronotropic effects?

Drugs and compounds with chronotropic effects change the heart rate and rhythm by affecting the electrical conduction system of the heart and the nerves that influence it. To study the cardiac safety of new drugs and compounds, PhysioStim now provides a new study model using a spontaneously beating isolated rat right atria.

Spontaneously beating isolated rat right atria

concentrations spontaneous atrial beating chronotropic effects

A quick way to test the chronotropic effects of your compounds

Rat atria pharmacological validation

Don’t hesitate to consult our page on isolated organ bath techniques to study cardiac contractility for more information.

Interested in our approach? Don't hesitate to contact us

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