Your expert in preclinical cardiac electrophysiology

High quality pharmacology & electrophysiology studies


GLP-certified expertise at your service

PhysioStim is a preclinical Contract Research Organization that specializes in cardiovascular pharmacology and electrophysiology studies for preclinical drug development purposes. We’re recognized as one of Europe’s most reliable CROs when it comes to cardiac safety. Our experts offer electrophysiological studies and preclinical resources as well as their dedicated expertise in answering ICH S7A and S7B guidelines in accordance with GLP (Good Laboratory Practices). We also respect the 3R principle and have already taken steps to comply with the upcoming CIPA guidelines.

We help pharmaceutical & biotech companies

Study the cardiovascular safety of a given compound

Derisk compounds at an early stage

Select the right Lead Candidate(s) during the preclinical stage

Determine early evaluation of compounds able to induce QT prolongation

Your expert in cardiac safety assays

Microscope icon


GLP-certified preclinical ICH S7B & S7A-compliant assays

Test vial icon


A wide range of in vitro and in vivo assays for cardiac safety studies

The right study model to guarantee excellence

A wide selection for reliable preclinical safety studies

The experts at PhysioStim go beyond standard study guidelines to conduct their safety studies. We provide a wide range of possibilities to conduct both mandatory and complementary studies and help your project move forward. PhysioStim has over 17 years of expertise in developing in vitro and ex vivo models to investigate potential drug-related cardiac adverse effects. We provide cellular models as well as tissue and organ models.

A dedicated team of pharmacology & electrophysiology specialists

PhysioStim has a history in excellence. Ever since our creation in 2000, our expert team continues to improve and refine their specialized know-how in cardiac safety pharmacology, electrophysiological studies and preclinical resources. Over the years, we have become one of Europe’s most reliable Contract Research Organizations in this area. 

National French agency for drug and health safety ANSM logo
OECD logo better policies for better lives
ICH preclinical study guidelines
CIPA initiative logo
3R logo Reduce Reuse Recycle

Latest news

For more information on our assays and services

Don’t hesitate to contact us